• Adding zooplankton to the OSMAC toolkit: Effect of grazing stress on the metabolic profile and bioactivity of a diatom 

      Osvik, Renate Døving; Ingebrigtsen, Richard Andre; Norrbin, Fredrika; Andersen, Jeanette Hammer; Eilertsen, Hans Christian; Hansen, Espen Holst (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-03)
      “One strain many compounds” (OSMAC) based approaches have been widely used in the search for bioactive compounds. Introducing stress factors like nutrient limitation, UV-light or cocultivation with competing organisms has successfully been used in prokaryote cultivation. It is known that diatom physiology is affected by changed cultivation conditions such as temperature, nutrient concentration and ...
    • Antimikrobielle forbindelser i marine diatomeer (kiselalger) 

      Osvik, Renate Døving (Master thesis; Mastergradsoppgave, 2013-05-15)
      Bioprospektering er definert som leting etter og karakterisering av nye bioaktive forbindelser fra naturens ressurser med den hensikt å benytte denne kunnskapen kommersielt til utvikling av medisiner, helsekost eller stoffer med annen anvendelse. Blant moderne medisiner er hele 40% basert kunnskap fra naturstoffer, og blant kreftmedisiner og medisiner mot infeksiøse sykdommer er andelen enda høyere. ...
    • Bacterial diversity of aMasi, a South African fermented milk product, determined by clone library and denaturing gradient gel electrophoresis analysis 

      Osvik, Renate Døving; Sperstad, Sigmund; Breines, Eva Marie; Hareide, ellinor; Godfroid, Jacques; Zhou, Zhigang; Ren, Pengfei; Geoghegran, Claire; Holzapfel, Wilhelm; Ringø, Einar (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      In the present study, we investigated the bacterial diversity of aMasi, a traditional South African fermented milk product, by 16S rRNA clone library and Denaturing Gradient Gel Electrophoresis (DGGE) analysis. Two hundred and eighty two clones from clone library were isolated and identified from aMasi, prepared from the milk of four cows from one herd in the EkuPindiseni Community, North West of ...
    • Bioactivity of a Marine Diatom (Porosira glacialis [Grunow] Jorgensen 1905) Cultivated With and Without Factory Smoke CO2 

      Osvik, Renate Døving; Andersen, Jeanette Hammer; Eilertsen, Hans Christian; Genevière, Anne-Marie; Hansen, Espen Holst (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-16)
      Using industrial emissions as a strategy for CO<sub>2</sub> sequestration through carbon capture and utilization (CCU) in cultivation of microalgae can potentially change cultivation factors such as pH, nutrient availability and presence of trace metals, which could alter the growth and metabolism of the microalgae. It is therefore important to investigate whether such changes in culturing conditions ...
    • Bioprospecting of marine phytoplankton from large scale cultivation - Effect of culture conditions on bioactivity and biochemistry of the diatom Porosira glacialis 

      Osvik, Renate Døving (Doctoral thesis; Doktorgradsavhandling, 2021-06-23)
      The diatoms make up the largest and most important group of marine microalgae. They are responsible for a quarter of all inorganic carbon fixation in the ocean and are thus of immense importance for global CO2 sequestration. This makes them good candidates for biological carbon capture and utilization (CCU) by mass cultivation using CO2 emissions from industrial point sources. Large scale cultivation ...
    • Genetic Inactivation of European Sea Bass (Dicentrarchus labrax L.) Eggs Using UV-Irradiation: Observations and Perspectives 

      Colléter, Julie; Penman, David J; Lallement, Stephane; Fauvel, Christian; Hanebrekke, Tanja Lexau; Osvik, Renate Døving; Eilertsen, Hans Christian; D'Cotta, Helena; Chatain, Beatrice; Peruzzi, Stefano (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
      Androgenesis is a form of uniparental reproduction leading to progenies inheriting only the paternal set of chromosomes. It has been achieved with variable success in a number of freshwater species and can be attained by artificial fertilization of genetically inactivated eggs following exposure to gamma (γ), X-ray or UV irradiation (haploid androgenesis) and by restoration of diploidy by suppression ...
    • Mass Cultivation of Microalgae: I. Experiences with Vertical Column Airlift Photobioreactors, Diatoms and CO2 Sequestration 

      Eilertsen, Hans Christian; Eriksen, Gunilla; Bergum, John-Steinar; Strømholt, Jo; Elvevoll, Edel O.; Eilertsen, Karl-Erik; Heimstad, Eldbjørg Sofie; Giæver, Ingeborg Hulda; Israelsen, Linn; Svenning, Jon Brage; Dalheim, Lars; Osvik, Renate Døving; Hansen, Espen Holst; Ingebrigtsen, Richard Andre; Aspen, Terje M; Wintervoll, Geir-Henning (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-17)
      From 2015 to 2021, we optimized mass cultivation of diatoms in our own developed vertical column airlift photobioreactors using natural and artificial light (LEDs). The project took place at the ferrosilicon producer Finnfjord AS in North Norway as a joint venture with UiT—The Arctic University of Norway. Small (0.1–6–14 m<sup>3</sup>) reactors were used for initial experiments and to produce inoculum ...